Resultados a largo plazo de la valvuloplastía mitral con balón.

Autores/as

  • Gonzalo Martínez R. Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile
  • Alejandro Fajuri N Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile
  • Samuel Córdova A Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile
  • Sandra Braun J Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile
  • Eugenio Marchant D Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile
  • Eduardo Guarda S. Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile
  • Nicolás Veas P Hospital Clínica Universidad Católica
  • Manuel Méndez L Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile
  • Dante Lindefjeld C Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile
  • Osvaldo Pérez P. Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile
  • Alejandra Flores Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile
  • Edith Valenzuela Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile
  • Alejandro Martínez S Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Palabras clave:

Balloon valvuloplasty, follow-up studies, Mitral valve stenosis

Resumen

Background: Mitral balloon valvuloplasty (MBV) is the therapy of choice for the treatment of symptomatic mitral stenosis with suitable anatomy. Although its short and mid-term results are favorable, there is a paucity of information about long-term follow-up. Aim: To assess the late results of MBV. Material and methods: A cohort of 225 patients aged 8 to 20 years who were subjected to a MBV from 1989 to 2001, was studied. All variables at the time of the procedure, short and long-term results and major events during follow-up (new mitral intervention and mortality) were recorded. Uni and multivariate analysis were used to assess prognosis. Results: The mean follow-up lapse was 13.5 years (range 8 to 20 years). During this period, 88 patients (39.1%) remained event-free and in acceptable functional capacity. Eight percent died, 8% required a second MBV and 43.5% required a surgical mitral valve replacement. A post-procedural area equal or greater to 1.9 cm2 was associated with a greater likelihood of free-event survival (log rank test: p=0.02 / Cox proportional regression model: coefficient 0.54, p=0.04). Conclusions: MBV is effective, although there is a high chance of new interventions in the long-term follow-up. A larger post-procedure mitral area is associated with a better prognosis.

Biografía del autor/a

Gonzalo Martínez R., Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Alejandro Fajuri N, Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Samuel Córdova A, Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Eugenio Marchant D, Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Eduardo Guarda S., Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Nicolás Veas P, Hospital Clínica Universidad Católica

Alejandro Martínez S. Departamento de Enfermedades Cardiovasculares Hospital Clínico Pontificia Universidad Católica de Chile E-mail: amartine@med.puc.cl

Manuel Méndez L, Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Dante Lindefjeld C, Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Background: Mitral balloon valvuloplasty (MBV) is the therapy of choice for the treatment of symptomatic mitral stenosis with suitable anatomy. Although its short and mid-term results are favorable, there is a paucity of information about long-term follow-up. Aim: To assess the late results of MBV. Material and methods: A cohort of 225 patients aged 8 to 20 years who were subjected to a MBV from 1989 to 2001, was studied. All variables at the time of the procedure, short and long-term results and major events during follow-up (new mitral intervention and mortality) were recorded. Uni and multivariate analysis were used to assess prognosis. Results: The mean follow-up lapse was 13.5 years (range 8 to 20 years). During this period, 88 patients (39.1%) remained event-free and in acceptable functional capacity. Eight percent died, 8% required a second MBV and 43.5% required a surgical mitral valve replacement. A post-procedural area equal or greater to 1.9 cm2 was associated with a greater likelihood of free-event survival (log rank test: p=0.02 / Cox proportional regression model: coefficient 0.54, p=0.04). Conclusions: MBV is effective, although there is a high chance of new interventions in the long-term follow-up. A larger post-procedure mitral area is associated with a better prognosis.

Osvaldo Pérez P., Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Alejandra Flores, Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Edith Valenzuela, Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Alejandro Martínez S, Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

Departamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile

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Publicado

2014-10-30

Cómo citar

Martínez R., G., Fajuri N, A., Córdova A, S., Braun J, S., Marchant D, E., Guarda S., E., Veas P, N., Méndez L, M., Lindefjeld C, D., Pérez P., O., Flores, A., Valenzuela, E., & Martínez S, A. (2014). Resultados a largo plazo de la valvuloplastía mitral con balón. Revista Médica De Chile, 142(11). Recuperado a partir de https://mail.revistamedicadechile.cl/index.php/rmedica/article/view/2966

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Artículos de Investigación

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