Hemangioendotelioma epitelioide y fusiforme de ganglio linfático. Caso Clínico.

Resumen

SPINDLE AND EPITHELIOID HAEMANGIOENDOTHELIOMA OF THE LYMPH NODE. REPORT OF ONE CASE

Primary vascular tumors of lymph nodes are extremely rare with the exception of AIDS-related Kaposi’s sarcoma. The diagnosis of epithelioid haemangioendothelioma (EH) is difficult to make without ancillary studies, since it is devoid of morphological features indicating its vascular nature and  it may be overlooked when it appears as a primary tumor of lymph nodes. Spindle and epithelioid haemangioendothelioma (SEH) is considered to be a variant of EH, which has been reported to occur exclusively in lymph nodes and the spleen. We report a 70 years old male with chronic lymphocytic leukemia (CLL) and left cervical lymphadenopathy. An excisional biopsy was performed, and microscopically the lymph node showed effacement of nodal architecture by a tumor composed of spindle cells disposed in intersecting fascicles, and characterized by abundant eosinophilic cytoplasm, elongated nuclei and conspicuous nucleoli. A second population of cells had an epithelioid appearance with intracytoplasmic vacuoles containing red blood cells. Immunohistochemically, the tumor cells were positive for CD31 and CD34. The final diagnosis was SEH of the lymph node.